Cetoenoles cíclicos sustituidos con cicloalquilfenilos

摘要

Cyclic keto enol derivatives (I) are new. Cyclic keto enol derivatives of formula (I) are new. In (I): J = optionally substituted (OS) (hetero)cycloalkyl; X, Y' = H, alkyl, halo, haloalkyl, alkoxy or haloalkoxy; m = 1-3; CKE = a cyclic keto enol group of formula (1)-(10). A = e.g. H; alkyl, alkenyl or alkoxyalkyl; B' = e.g. H, alkyl or alkoxyalkyl; or D' = H or OS alkyl, alkenyl or alkynyl; Q 1> = e.g. H, alkyl or alkoxyalkyl; Q 2>, Q 4>, Q 5>, Q 6> = H or alkyl; Q 3> = e.g. H, alkyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl or phenyl; G = e.g. H, COR 1> or E; E = a metal ion or ammonium; R 1> = e.g. alkyl, alkenyl, alkoxyalkyl or alkylthioalkyl. Provided that at least 1 of J, X or Y' = is in the 2-position of the phenyl moiety and is not H. Full definitions are given in the Definitions field. Independent claims are also included for: (1) a process for preparing (I); (2) composition comprising at least one compound (I) and at least one safener comprising a compound for formula (IIa-e), or one of 57 specific compounds listed in the specification; and (3) starting materials and intermediates of formulae (II), (III), (IV), (VI), (VIII), (IX), (XII), (XIII), (XIV), (XXVIII), (XXVII), (XXXII), (XXXIV), (XXXVI), (XI), (XXXVII), (XXXVIII), (XLI), (XLII) and (LXVI). In the safeners (IIa-e): m = 0-5; A 1> = a group of formula (a)-(d); n = 0-5; A 2> = OS 1-2C alkanediyl; R 14>, R 15> = e.g. OH or SH; R 16> = OS 1-4C alkyl; R 17>, R 18> = e.g. H or OS 1-6C alkyl, 2-6C alkenyl or 2-6C alkynyl; R 19> = e.g. H, CN or halo; R 20> = e.g. H or OS 1-6C alkyl; R 21> = e.g. H, CN or halo; X 1> = e.g. nitro, CN or halo; X 2>, X 3> = H or as for X 1>; t = 0-5; v = 0-5 (sic); R 22>, R 23> = H or 1-4C alkyl R 24> = e.g. H or OS 1-6C alkyl or 1-6C alkoxy; R 25> = e.g. H or OS 1-4C alkyl; R 26> = as for R 25>; or OS phenyl; and X 4>, X 5> = e.g. nitro, CN or COOH. Full definitions are included in the Definitions field. In the claimed starting materials and intermediates: Ar = phenyl substituted with X, Y' and (J) m; R 8> = alkyl; Ar' = phenyl optionally monosubstituted with halo, alkyl or alkoxy; Hal = halo; Z = a leaving group; U' = OR 8>, V'=H, halo, alkyl or alkoxy; and all other groups are as listed for (I). [Image] [Image] [Image] [Image] [Image] [Image] [Image] [Image] [Image] [Image] [Image] - ACTIVITY : Herbicide; Insecticide; Arachnicide; Molluscicide; Anthelmintic; Protozoacide; Nematocide. In a post-emergence test, 3-(4-cyclopropyl-2-ethyl-6-methyl-phenyl)-8-methoxy-2-oxo-1-aza-spiro [4.5]dec-3-en-4-yl carbonate ethyl ester gave at least 90% control of Lolium multiflorum and Setaria viridis at an application rate of 320 g/ha. - MECHANISM OF ACTION : None given.