发明名称 |
MOUSE ARTIFICIAL CHROMOSOME VECTOR |
摘要 |
Disclosed is a mouse artificial chromosome vector, comprising: a natural centromere derived from a mouse chromosome; a mouse-chromosome-derived long-arm fragment formed by deleting a long-arm distal region at a mouse chromosome long-arm site proximal to the centromere; and a telomere sequence, wherein the vector is stably retained in a cell and/or tissue of a mammal. In addition, disclosed are cells or non-human animals comprising the vector, and use of the cells or non-human animals. |
申请公布号 |
EP2522725(A4) |
申请公布日期 |
2013.09.25 |
申请号 |
EP20110731868 |
申请日期 |
2011.01.06 |
申请人 |
NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY;CHROMOCENTER INC. |
发明人 |
OSHIMURA, MITSUO;KAZUKI, YASUHIRO;TAKIGUCHI, MASATO;MATSUOKA, TAKASHI |
分类号 |
C12N15/00;A01K67/027;C12N5/0735;C12N5/074;C12N15/09;C12N15/10;C12N15/873 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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