发明名称 METHOD OF DETERMINING A CHEMOTHERAPEUTIC REGIMEN BASED ON ERCC1 EXPRESSION
摘要 <p>The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing ERCC1 expression levels in fixed or fixed and paraffin embedded tissues and determine a platinum-based chemotherapy by examination of the amount of ERCC1 mRNA in a patient's tumor cells and comparing it to a predetermined threshold expression level. More specifically, the invention provides to oligonucleotide primer pair ERCC1 and methods comprising their use for detecting levels of ERCC1 mRNA.</p>
申请公布号 EP1364054(B1) 申请公布日期 2013.09.25
申请号 EP20010998006 申请日期 2001.11.29
申请人 RESPONSE GENETICS, INC. 发明人 DANENBERG, KATHLEEN, D.
分类号 C12Q1/68;G01N33/50;A61K31/7068;A61K33/24;A61P35/00;C12N15/09;C12Q;G01N33/574 主分类号 C12Q1/68
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