发明名称 |
Substituted isoquinolines and isoquinolinones as Rho kinase inhibitors |
摘要 |
The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
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申请公布号 |
US8541449(B2) |
申请公布日期 |
2013.09.24 |
申请号 |
US200913000754 |
申请日期 |
2009.06.19 |
申请人 |
PLETTENBURG OLIVER;LORENZ KATRIN;WESTON JOHN;LOEHN MATTHIAS;KLEEMANN HEINZ-WERNER;DUCLOS OLIVIER;JEANNOT FREDERIC;SANOFI |
发明人 |
PLETTENBURG OLIVER;LORENZ KATRIN;WESTON JOHN;LOEHN MATTHIAS;KLEEMANN HEINZ-WERNER;DUCLOS OLIVIER;JEANNOT FREDERIC |
分类号 |
C07D217/24;A61K31/472 |
主分类号 |
C07D217/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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