| 发明名称 |
WORTMANNIN ANALOGS AND METHODS OF USING SAME IN COMBINATION WITH CHEMOTHERAPEUTIC AGENTS |
| 摘要 |
Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic agents in the treatment of cancer.
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| 申请公布号 |
CA2578336(C) |
申请公布日期 |
2013.09.24 |
| 申请号 |
CA20052578336 |
申请日期 |
2005.07.11 |
| 申请人 |
PROLX PHARMACEUTICALS CORP.;ARIZONA BOARD OF REGENTS, ACTING ON BEHALF OF THEUNIVERSITY OF ARIZONA;UNIVERSITY OF PITTSBURGH |
发明人 |
KIRKPATRICK, LYNN;POWIS, GARTH;WIPF, PETER |
| 分类号 |
A61K31/40;A61K31/35;C07D311/78 |
主分类号 |
A61K31/40 |
| 代理机构 |
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