发明名称 |
SELECTIVE CELL TARGETING USING ADENOVIRUS AND CHEMICAL DIMERS |
摘要 |
<p>Compositions and methods for retargeting adenovirus to a cell using chemical dimers are provided. In particular a recombinant adenovirus comprising a nucleic acid comprising a capsid-dimerizing agent binder conjugate and a ligand-dimerizing agent binder conjugate is provided.</p> |
申请公布号 |
CA2867129(A1) |
申请公布日期 |
2013.09.19 |
申请号 |
CA20132867129 |
申请日期 |
2013.03.13 |
申请人 |
SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
O'SHEA, CLODAGH;MIYAKE-STONER, SHIGEKI;POWERS, COLIN |
分类号 |
C12N15/62;A61P35/00;C12N15/34 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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