发明名称 |
Compositions And Methods For Inhibiting Expression Of The HAMP Gene |
摘要 |
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the HAMP gene (HAMP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the HAMP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by HAMP gene expression and the expression of the HAMP gene using the pharmaceutical composition.
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申请公布号 |
US2013243849(A1) |
申请公布日期 |
2013.09.19 |
申请号 |
US201313900854 |
申请日期 |
2013.05.23 |
申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
NAKAYAMA TOMOKO;GEICK ANKE;TAN PAMELA;LIN HERBERT Y. |
分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
代理机构 |
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地址 |
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