发明名称 NOVEL COMPOUND AND MEDICAL USE THEREOF
摘要 Provided is a levodopa prodrug that overcomes the problems attributed to the blood kinetics of levodopa such as large number of doses and the incidence of side effects due to frequent dosing. (2S)-2-Amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid, a salt thereof, or a solvate thereof is a levodopa prodrug, and provides a flat blood concentration-time profile of levodopa through oral administration, and therefore is useful as a preventive and/or therapeutic agent for Parkinson's disease and/or Parkinson's syndrome that overcomes the problems associated with pharmaceutical preparations of levodopa.
申请公布号 US2013245074(A1) 申请公布日期 2013.09.19
申请号 US201113991025 申请日期 2011.12.01
申请人 KOKUBO MASAYA;YANO KOJI;ONO PHARMACEUTICALS CO., LTD. 发明人 KOKUBO MASAYA;YANO KOJI
分类号 A61K31/198;A61K45/06;C07C229/36 主分类号 A61K31/198
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