发明名称 |
SANDWICH ASSAY FOR IMMUNOSUPPRESSANT DRUGS |
摘要 |
Methods are disclosed for determining an immunosuppressant drug in a sample suspected of containing an immunosuppressant drug. The method includes providing in combination in a medium the sample, a first monoclonal antibody for the immunosuppressant drug, and a second monoclonal antibody for the immunosuppressant drug. The second monoclonal antibody binds to a portion of the immunosuppressant drug other than the portion to which the first monoclonal antibody binds to the immunosuppressant drug. The medium is incubated under conditions for binding of the first monoclonal antibody and the second monoclonal antibody to the immunosuppressant drug. The medium is examined for the presence of an immunocomplex comprising the immunosuppressant drug, the first monoclonal antibody and the second monoclonal antibody. The presence and/or amount of the immunocomplex indicates the presence and/or amount of the immunosuppressant drug in the sample. |
申请公布号 |
WO2013133917(A1) |
申请公布日期 |
2013.09.12 |
申请号 |
WO2013US24054 |
申请日期 |
2013.01.31 |
申请人 |
SIEMENS HEALTHCARE DIAGNOSTICS INC.;WEI, TIE, QUAN |
发明人 |
WEI, TIE, QUAN |
分类号 |
G01N33/53;C07K16/00;C12P21/08 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|