发明名称 |
VACCINES FOR PREVENTING MENINGOCOCCAL INFECTIONS |
摘要 |
The present invention stems from the finding that the interaction between the beta2 adrenoceptor (beta2AP) and type IV pilus-associated proteins initiates a process leading to the opening of the blood-brain barrier. The invention therefore pertains to a vaccine for preventing the spreading of meningococci into the meningeal space, wherein said vaccine allows the production of antibodies inhibiting the interaction between the type IV pilus-associated proteins and the beta2AP. |
申请公布号 |
EP2635593(A1) |
申请公布日期 |
2013.09.11 |
申请号 |
EP20110778646 |
申请日期 |
2011.11.04 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITE PARIS DESCARTES |
发明人 |
COUREUIL, MATHIEU;NASSIF, XAVIER;MARULLO, STEFANO |
分类号 |
A61K39/095;C07K14/22;C07K19/00;C12N15/62 |
主分类号 |
A61K39/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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