发明名称 Pyrazolyl piperidine compounds as T-type calcium channel antagonists
摘要 PURPOSE: A pharmaceutical composition containing pyrazoyl piperidine compounds and pharmaceutically acceptable salt thereof is provided to prevent or treat brain diseases, heard diseases, cancer, and pain. CONSTITUTION: A pyrazoyl piperidine compound is denoted by chemical formula 1. A pharmaceutical composition for treating cerebral diseases, cardiac diseases, cancer, or pain contains the compound of chemical formula 1 as an active ingredient. A method for preparing the compound comprises: a step of reacting piperidine acetate of chemical formula 2 and pyrazole methyl amine of chemical formula 3 of a step of reacting piperidine compound of chemical formula 4 with an aldehyde compound of chemical formula 5 by reduction-amination. [Reference numerals] (AA) Reductive amination
申请公布号 KR101306271(B1) 申请公布日期 2013.09.09
申请号 KR20110016787 申请日期 2011.02.24
申请人 发明人
分类号 A61K31/454;A61P25/00;C07D401/12 主分类号 A61K31/454
代理机构 代理人
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