| 摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition including a novel crystalline form of the pitavastatin calcium and the crystalline form.SOLUTION: There is provided a crystal polymorphism A having a feature peak in an X-ray powder diffraction figure, a water content of 3-15% (however, 3-12% is excluded), and a (3R, 5S)-7-[ 2-cyclopropyl -4-( 4- fluorophenyl ) quinoline-3-yl]-3, 5-dihydroxy-6(E)-heptenoic acid hemi calcium salt measured by thermogravimetry that in combination with FT-IR spectroscopy. |
