| 发明名称 |
PYRAZOL-1-YL BENZENE SULFONAMIDES AS CCR9 ANTAGONISTS |
| 摘要 |
<p>Compounds of formula (I) are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.</p> |
| 申请公布号 |
CA2865714(A1) |
申请公布日期 |
2013.09.06 |
| 申请号 |
CA20132865714 |
申请日期 |
2013.02.28 |
| 申请人 |
CHEMOCENTRYX, INC. |
发明人 |
CHEN, XI;FAN, JUNFA;FAN, PINGCHEN;KRASINSKI, ANTONI;LI, LIANFA;LUI, REBECCA M.;MCMAHON, JEFFREY P.;POWERS, JAY P.;ZENG, YIBIN;ZHANG, PENGLIE |
| 分类号 |
C07D401/04;A61K31/4709;A61K31/4725;A61K31/502;A61K31/517;A61P1/00;A61P11/00;A61P17/00;A61P19/00;A61P29/00;A61P35/00;A61P37/00;C07D231/42;C07D401/06;C07D403/04 |
主分类号 |
C07D401/04 |
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