METHOD FOR BINDING EXOGENOUS MOLECULE TO CELLULAR CHROMATIN

摘要

PROBLEM TO BE SOLVED: To provide methods for binding an exogenous molecule to a binding site within a region of interest in cellular chromatin and methods for identifying the binding site in the cellular chromatin for the exogenous molecule.SOLUTION: Methods include the steps of identification of one or more accessible regions in cellular chromatin, identification of a target site within the accessible region, introduction of an exogenous molecule into a cell, and testing for the binding of the exogenous molecule to a binding site.