| 发明名称 |
Acylsulfonamides and processes for producing the same |
| 摘要 |
The present disclosure relates to acylsulfonamides and processes for their preparation. The processes involve a target-guided synthesis approach, whereby a thioacid and a sulfonyl azide are reacted in the presence of a biological target protein, a Bcl-2 family protein, to form the acylsulfonamide.
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| 申请公布号 |
US8524947(B2) |
申请公布日期 |
2013.09.03 |
| 申请号 |
US20090867812 |
申请日期 |
2009.02.23 |
| 申请人 |
WANG HONG-GANG;MANETSCH ROMAN;HU XIANGDONG;KULKARNI SAMEER;SUN JIAZHI;UNIVERSITY OF SOUTH FLORIDA;H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. |
发明人 |
WANG HONG-GANG;MANETSCH ROMAN;HU XIANGDONG;KULKARNI SAMEER;SUN JIAZHI |
| 分类号 |
C07C321/00;C07D211/06;C07D217/02;C07D277/00 |
主分类号 |
C07C321/00 |
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