Antibodies to the alpha-7 nicotinic receptors and methods of treating inflammatory disorders with the same

摘要

An antibody or an antigen binding fragment thereof which binds to mammalian alpha7 subunit of a nicotinic acetylcholine receptor or its functional variant and which is an agonist of said receptor or variant. Pharmaceutical compositions comprising same. A method of treating a subject suffering from an inflammatory condition comprising administering to said subject an antibody or an antigen-binding fragment as described herein.