发明名称 |
TRIAZOLE DERIVATIVES AS MITOCHONDRIAL FUNCTION MODULATORS |
摘要 |
PURPOSE: A triazole derivative is provided to be used as a restorative of mitochondrial dysfunction with effects of treating Alzheimer's diseases, Parkinson's disease, Huntington's disease, ischemic diseases, diabetes, and schizophrenia. CONSTITUTION: A compound is selected among a triazole derivative of chemical formula 1and a pharmaceutically acceptable salt thereof. A pharmaceutical composition for treating Alzheimer's disease, Parkinson's disease, Huntington's disease, ischemic disease, diabetes, and schizophrenia contains the compound as an active ingredient. A method for preparing the triazole compound comprises the step of reacting an azide compound of chemical formula 2 and an ethynyl benzene compound of chemical formula 3 by dipolar cycloaddition. |
申请公布号 |
KR20130096900(A) |
申请公布日期 |
2013.09.02 |
申请号 |
KR20120018466 |
申请日期 |
2012.02.23 |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
MIN, SUN JOON;CHO, YONG SEO;PAE, AE NIM;LEE, JAE KYUN;LEE, JI YOUN;JUNG, SUN HWA;PARK, BEOUNG GUN |
分类号 |
C07D403/04;A61K31/4025;A61K31/41;C07D249/06 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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