发明名称 NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF
摘要 600788 Disclosed herein is a compound of general formula (I), wherein the variables are defined in the specification, and the use thereof in the treatment of fungal infections, specifically wherein said fungal infection is from Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger, Scopulariopsis Brevicaulis or Candida, such as Candida Albicans or Candida Glabrata. Specific embodiments of the compound include: 8-hydroxy-N-methyl-N-(4-(2-phenylpropan-2-yl)benzyl)quinoline-2-carboxamide, (8-hydroxyquinolin-7-yl)(morpholino)methanone, N-(2-cyanoethyl)-N-(furan-2-ylmethyl)-S-hydroxyquinoline-7-carboxamide, and (S-Bromo-8-hydroxyquinolin-7-yl)(isoindolin-2-yl)methanone.
申请公布号 NZ600788(A) 申请公布日期 2013.08.30
申请号 NZ20100600788 申请日期 2010.12.28
申请人 POLICHEM S.A. 发明人 GAGLIARDI, STEFANIA;LEGORA, MICHELA;MAILLAND, FEDERICO;DEL SORDO, SIMONE
分类号 C07D215/48;A61K31/4709;A61P31/10;C07D401/06;C07D401/12;C07D407/06;C07D407/12;C07D417/06;C07D491/113 主分类号 C07D215/48
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