摘要 |
600788 Disclosed herein is a compound of general formula (I), wherein the variables are defined in the specification, and the use thereof in the treatment of fungal infections, specifically wherein said fungal infection is from Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger, Scopulariopsis Brevicaulis or Candida, such as Candida Albicans or Candida Glabrata. Specific embodiments of the compound include: 8-hydroxy-N-methyl-N-(4-(2-phenylpropan-2-yl)benzyl)quinoline-2-carboxamide, (8-hydroxyquinolin-7-yl)(morpholino)methanone, N-(2-cyanoethyl)-N-(furan-2-ylmethyl)-S-hydroxyquinoline-7-carboxamide, and (S-Bromo-8-hydroxyquinolin-7-yl)(isoindolin-2-yl)methanone.
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