PROTECTION, RESTORATION AND ENHANCEMENT OF ERYTHROPOIETIN-RESPONSIVE CELL, TISSUE AND ORGAN

摘要

PROBLEM TO BE SOLVED: To provide methods and compositions for protecting or enhancing an erythropoietin-responsive cell, tissue, organ or body part function or viability in vivo, in situ or ex vivo.SOLUTION: This erythropoietin does not have sialic acid components at least, or does not have N-bonded sugar chains or O-bonded sugar chains at least. Pharmaceutical compositions contain modified erythropoietin having at least one or more of modified lysine residue groups and pharmaceutically acceptable carriers.