发明名称 |
METHOD FOR LARGE SCALE PREPARATION OF THE ACTIVE DOMAIN OF HUMAN PROTEIN TYROSINE PHOSPHATASE WITHOUT FUSION PROTEIN |
摘要 |
The present invention relates to methods for identifying inhibitors or activators of protein tyrosine phosphatase (PTP). In some examples, the methods utilize a PTP active domain with high activity and stability expressed without help of a fusion protein, by using computer based protein structure prediction technique. PTP prepared by the disclosed method may also be used as an antigen protein for the construction of a selective antibody and as a protein for the studies of PTP structure and functions.
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申请公布号 |
US2013224779(A1) |
申请公布日期 |
2013.08.29 |
申请号 |
US201313772708 |
申请日期 |
2013.02.21 |
申请人 |
BIOTECHNOLOGY KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
RYU SEONG EON;JEONG DAE GWIN;KIM JAE HOON;KIM SEUNG JUN;CHUNG SANG JEON;SON JEONG HEE |
分类号 |
C12Q1/42 |
主分类号 |
C12Q1/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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