| 摘要 |
Ra8 x z R7 N 0-CH2 N Formula I Provided are pyrrolo[l,2-fj[1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2 f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates 5 and prodrugs thereof, wherein the I ' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections. Formula (I), each XI or X2 is independently C-Ri" or N. |
