BOUVARDIN DERIVATIVES AND THERAPEUTIC USES THEREOF
摘要
The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
申请公布号
WO2013126617(A1)
申请公布日期
2013.08.29
申请号
WO2013US27200
申请日期
2013.02.21
申请人
THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODYCORPORATE;SUVICA, INC.;SU, TIN, TIN;GLADSTONE, MARA, N.;ZHANG, GAN;SAMMAKIA, TAREK
发明人
SU, TIN, TIN;GLADSTONE, MARA, N.;ZHANG, GAN;SAMMAKIA, TAREK