摘要 |
The present invention relates to a method for identifying a subject suffering from hepatitis B virus (HBV) infection as being susceptible to interferon treatment, said method comprising the steps of a) determining, in a sample of said subject, the amount of HBV immune complexes, b)comparing the amount of HBV immune complexes obtained in step a) to a reference value, and c) identifying a subject suffering from HBV infection as being susceptible to interferon treatment based on the result of the comparison made in step b). The present invention further relates to the use of the determination of the amount of HBV immune complexes in a sample from a subject suffering from HBV infection and of a detection agent for HBV immune complexes for identifying a subject suffering from HBV infection as being susceptible to interferon treatment. Furthermore, the present invention relates to a device and a kit allowing identifying a subject suffering from HBV infection as being susceptible to interferon treatment. |
申请人 |
ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG;ACADEMIC MEDICAL CENTER AT THE UNIVERSIITY OF AMSTERDAM;KLAUSE, URSULA;HIPP, BERTHOLD;GRUNERT, VEIT PETER;UPMEIER, BARBARA;LOPATIN, URI;DE NIET, ANNIKKI;REESINK, HENK;ZAAIJER, HANS |
发明人 |
KLAUSE, URSULA;HIPP, BERTHOLD;GRUNERT, VEIT PETER;UPMEIER, BARBARA;LOPATIN, URI;DE NIET, ANNIKKI;REESINK, HENK;ZAAIJER, HANS |