Disclosed herein are methods and compositions for targeted integration of sequences of interest such as lineage-specific or cell fate reporter constructs or protein encoding sequences into stem cells.
申请公布号
EP2419511(A4)
申请公布日期
2013.08.28
申请号
EP20100761996
申请日期
2010.04.08
申请人
SANGAMO BIOSCIENCES, INC.;THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
发明人
GREGORY, PHILIP, D.;HOCKEMEYER, DIRK;HOLMES, MICHAEL C.;JAENISH, RUDOLF;SOLDNER, FRANK;URNOV, FYODOR;YAO, SHUYUAN