发明名称 |
Process for preparation of (e)-5-(2-bromovinyl)-2'-deoxyuridine |
摘要 |
Process of preparing (E)-5-(2-bromovynyl)-2'-deoxyuridine (Brivudine) characterized in that halogen-free solvent selected form esters or cyclic ethers are used in the bromination step of 5-ethyl-2'-deoxyuridine diacylate. The use of solvents is advantageous in respect of toxicity, discharge costs and environment protection.
|
申请公布号 |
HU229136(B1) |
申请公布日期 |
2013.08.28 |
申请号 |
HU20030003323 |
申请日期 |
2002.02.21 |
申请人 |
MENARINI RICERCHE S.P.A.;BERLIN-CHEMIE AG |
发明人 |
SALIMBENI ALDO;MAGGI CARLO ALBERTO;MANZINI STEFANO;TUROZZI DAMIANO |
分类号 |
C07H19/073;C07B61/00;C07H19/06 |
主分类号 |
C07H19/073 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|