发明名称 |
HIGH THROUGHPUT DEVICE FOR SCREENING CANDIDATE COMPOUNDS FOR ACTIVITY AGAINST TARGET ION CHANNELS |
摘要 |
A high throughput screening device may comprise high-transmittance wells, electrodes disposed in the wells, and optical detection means. The device may be configured to apply an electric field in the wells to alter the transmembrane potential of cells disposed in the wells and produce detectable light emissions corresponding to ion channel activity.
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申请公布号 |
CA2763047(C) |
申请公布日期 |
2013.08.27 |
申请号 |
CA20012763047 |
申请日期 |
2001.07.09 |
申请人 |
VERTEX PHARMACEUTICALS (SAN DIEGO) LLC |
发明人 |
MAHER, MICHAEL P.;GONZALEZ, JESUS E., III |
分类号 |
C12M1/42;C12M1/34;C12Q1/02;C40B60/12;G01N21/03;G01N21/15;G01N33/483;G01N33/50;G01N33/68;G01N35/00 |
主分类号 |
C12M1/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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