发明名称 Cyclohexyl-azetidinyl antagonists of CCR2
摘要 The present invention comprises compounds of Formula I. wherein: R1, R2, R4, J, Q, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
申请公布号 US8518969(B2) 申请公布日期 2013.08.27
申请号 US201113161572 申请日期 2011.06.16
申请人 LANTER JAMES C.;MARKOTAN THOMAS P.;SUBASINGHE NALIN;SUI ZHIHUA;JANSSEN PHARMACEUTICA NV 发明人 LANTER JAMES C.;MARKOTAN THOMAS P.;SUBASINGHE NALIN;SUI ZHIHUA
分类号 A01N43/42;A61K31/47 主分类号 A01N43/42
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