发明名称 |
Centromere Detector and Method for Determining Radiation Exposure From Chromosome Abnormalities |
摘要 |
A method for determining radiation exposure from chromosome abnormalities present in a specimen by determining the location or locations of the centromere of each chromosome in a cell in an image of a metaphase cell by segmentation of an accurately drawn chromosome centerline followed by selection of a longitudinal cross-section with the minimum width or intensity or width and intensity; counting the number of centromeres in each chromosome in each cell; computing the frequency of dicentric chromosomes in a population of cells; and determining the radiation dose by comparing the computed frequency of dicentric chromosomes with a previously determined dose-response curve from a calibrated source. |
申请公布号 |
US2013216118(A1) |
申请公布日期 |
2013.08.22 |
申请号 |
US201113822289 |
申请日期 |
2011.11.04 |
申请人 |
ROGAN PETER KEITH;KNOLL JOAN HELEN;SAMARABANDU JAGATH;SUBASINGHE AKILA |
发明人 |
ROGAN PETER KEITH;KNOLL JOAN HELEN;SAMARABANDU JAGATH;SUBASINGHE AKILA |
分类号 |
G06F19/16 |
主分类号 |
G06F19/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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