发明名称 |
Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use |
摘要 |
Compositions and methods are provided for forming tissue-adherent hydrogels using substantially dry precursors. The dehydrated precursors are premixed prior to in situ therapy and utilize naturally-occurring body fluids as an aqueous environment that initiates transformation, which causes dissolution and nearly simultaneous crosslinking of the precursors, thus forming an insoluble hydrogel implant. The dehydrated precursor-based hydrogels may be used as sealants for fluid leaks from tissue, as adherent drug delivery depots, as means for augmenting and/or supporting tissue, and as means for serving a variety of other useful medical and surgical purposes.
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申请公布号 |
US8512749(B2) |
申请公布日期 |
2013.08.20 |
申请号 |
US20040795132 |
申请日期 |
2004.03.05 |
申请人 |
SAWHNEY AMARPREET S.;EDELMAN PETER G.;BENNETT STEVEN L.;INCEPT, LLC |
发明人 |
SAWHNEY AMARPREET S.;EDELMAN PETER G.;BENNETT STEVEN L. |
分类号 |
A61K9/14;A61F2/00;A61F2/02;A61K9/00;A61K9/70;A61K47/34;A61L24/00 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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