| 发明名称 |
METHODS OF INCORPORATING AMINO ACID ANALOGS INTO PROTEINS |
| 摘要 |
The invention provides a method of incorporating nonstandard amino acids into a protein by utilizing a modified aminoacyl-tRNA synthetase to charge the nonstandard amino acid to a modified tRNA, which forms strict Watson-Crick base-pairing with a codon that normally forms wobble base-pairing with natural tRNAs.
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| 申请公布号 |
US2013210073(A1) |
申请公布日期 |
2013.08.15 |
| 申请号 |
US201213730116 |
申请日期 |
2012.12.28 |
| 申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY;CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
KWON INCHAN;TIRRELL DAVID |
| 分类号 |
C12P21/00;C07H21/02;C07H21/04;C07K14/00;C12N1/18;C12N1/21;C12N9/00;C12N15/70;C12N15/74;C12P21/02;C12P21/06 |
主分类号 |
C12P21/00 |
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