发明名称 |
Compositions and Methods for Treating Glioblastoma GBM |
摘要 |
Methods of treating a malignant glioma in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a viral vector comprising: (i) a first polynucleotide sequence encoding a Fas-chimera (Fas-c), said first polynucleotide sequence comprising SEQ ID NOs: 2 and 3; and (ii) a second polynucleotide sequence encoding an endothelial cell-specific promoter or a periendothelial cell-specific promoter.
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申请公布号 |
US2013209450(A1) |
申请公布日期 |
2013.08.15 |
申请号 |
US201113520452 |
申请日期 |
2011.01.05 |
申请人 |
COHEN YAEL;BANGIO LIVNAT;BRENNER ANDREW J.;BREITBART EYAL |
发明人 |
COHEN YAEL;BANGIO LIVNAT;BRENNER ANDREW J.;BREITBART EYAL |
分类号 |
A61K38/17;A61K39/395;A61K48/00;A61N5/10 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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