GLYCOSYLATED ANTITUMOR ETHER LIPIDS AS NOVEL CANCER STEM CELL CYTOTOXIC AGENTS
摘要
<p>Glycosylated antitumor ether lipids (GAELs) are effective cytotoxic agents against cancer stem cells. Furthermore, combining GAELs which kill cells by a caspase-independent pathway with agents that kill cells by apoptosis will lead to elimination of the differentiated tumor cells and the undifferentiated cancer stem cells leading to an elimination of the tumor and preventing recurrence.</p>
申请公布号
WO2013116949(A1)
申请公布日期
2013.08.15
申请号
WO2013CA50105
申请日期
2013.02.08
申请人
UNIVERSITY OF MANITOBA;ARTHUR, GILBERT;SCHWEIZER, FRANK;SAMADDER, PRANATI;XU, YAOZU