发明名称 |
(PYRAZOL-3-YL)-1,3,4-THIADIAZOL-2-AMINE AND (PYRAZOL-3-YL)-1,3,4-THIAZOL-2-AMINE COMPOUNDS |
摘要 |
<p>A compound of Formula (I) wherein: either X is N and Y is CR5 or X is C and Y is S; Z is selected from N and CH; R1 is selected from H and Me; R2 is selected from H, OH, OMe and Me; each R3 is independently selected from C1-3alkyl, F, Cl, Br, CF3 and NH2; R4 is selected from Me, CF3, NO2 and CHF2; R5 is selected from H, Me and CHF2; R6 is selected from H and Me; and p is 0-3, compositions containing them, their use in therapy, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.</p> |
申请公布号 |
EP2419426(B1) |
申请公布日期 |
2013.08.14 |
申请号 |
EP20100716288 |
申请日期 |
2010.04.13 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
BALLELL PAGES, LLUIS;CASTRO PICHEL, JULIA;FERNANDEZ MENENDEZ, RAQUEL;FERNANDEZ VELANDO, ESTHER, PILAR;GONZALEZ DEL VALLE, SILVIA;LEON DIAZ, MARIA, LUISA;MENDOZA LOSANA, ALFONSO;WOLFENDALE, MATTHEW, JAMES |
分类号 |
C07D417/14;A61K31/425;A61K31/427;A61P11/00;A61P31/06 |
主分类号 |
C07D417/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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