发明名称 BIO SURFACE ACOUSTIC WAVE (SAW) RESONATOR AMPLIFICATION WITH NANOPARTICLES FOR DETECTION OF A TARGET ANALYTE
摘要 <p>The present invention relates generally to a signal amplification method for a SAW resonator microsensor for analyzing test samples, containing target analyte including proteins and nucleic acids. The method comprising the steps: reacting the analyte in a sample with a first molecular recognition component and a second molecular recognition component linked to at least one nanoparticle; and adding an enhancement solution comprising silver ions and/or gold ions, and a reducing agent, whereby the silver ions and/or gold ions are reduced to metallic silver and/or gold which is deposited onto the surface of the at least one nanoparticle; wherein the mass increase of the at least one nanoparticle is detected by a SAW sensor.</p>
申请公布号 EP2156185(B1) 申请公布日期 2013.08.14
申请号 EP20080758211 申请日期 2008.06.02
申请人 ATONOMICS A/S 发明人 WARTHOE, PETER
分类号 G01N33/53;G01N33/543;G01N33/553 主分类号 G01N33/53
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