发明名称 |
Tuberculosis diagnostic test |
摘要 |
A method of diagnosing in a host infection by or exposure to a mycobacterium which expresses ESAT-6 comprising (i) contacting a population of T cells from the host with one or more peptides or analogues selected from the peptides represented by SEQ ID NO:1 to 11 and analogues thereof which can bind a T cell receptor which recognises any of the said peptides, and (ii) determining whether the T cells of said T cell population recognise the peptide(s) and/or analogue(s). The method may performed in vivo. Peptides and a kit which enable the method to be carried out are provided.
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申请公布号 |
US8507211(B2) |
申请公布日期 |
2013.08.13 |
申请号 |
US201213489621 |
申请日期 |
2012.06.06 |
申请人 |
LALVANI AJIT;PATHAN ANSAR;ISIS INNOVATION LIMTIED |
发明人 |
LALVANI AJIT;PATHAN ANSAR |
分类号 |
G01N33/53;A61K38/00;A61K48/00;A61K49/00;C07K14/35;C12N15/09;C12Q1/02;C12R1/32;G01N33/554;G01N33/567;G01N33/569 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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