发明名称 Glucagon receptor modulators
摘要 The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
申请公布号 US8507533(B2) 申请公布日期 2013.08.13
申请号 US201213367459 申请日期 2012.02.07
申请人 ASPNES GARY ERIK;DIDIUK MARY THERESA;FILIPSKI KEVIN JAMES;GUZMAN-PEREZ ANGEL;LEE ESTHER CHENG YIN;PFEFFERKORN JEFFREY ALLEN;STEVENS BENJAMIN DAWSON;TU MEIHUA MIKE;PFIZER INC. 发明人 ASPNES GARY ERIK;DIDIUK MARY THERESA;FILIPSKI KEVIN JAMES;GUZMAN-PEREZ ANGEL;LEE ESTHER CHENG YIN;PFEFFERKORN JEFFREY ALLEN;STEVENS BENJAMIN DAWSON;TU MEIHUA MIKE
分类号 A61K31/415;C07D231/12 主分类号 A61K31/415
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