发明名称 |
HYBRID NANOPORE DEVICE WITH OPTICAL DETECTION AND METHODS OF USING SAME |
摘要 |
The invention is directed to a device comprising a protein nanopore immobilized in a lipid layer within an aperture of a solid phase substrate, which provides a stable platform for using first and second members of one or more FRET pairs to generate optical signals as a labeled analyte translocates through the bore of the protein nanopore. In another aspect, the invention is directed to the use of the device to determine the nucleotide sequence of a polynucleotide analyte.
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申请公布号 |
US2013203050(A1) |
申请公布日期 |
2013.08.08 |
申请号 |
US201213662532 |
申请日期 |
2012.10.28 |
申请人 |
QUANTAPORE, INC.;QUANTAPORE, INC. |
发明人 |
HUBER MARTIN;CLANCY BASON E.;HALL ADAM R. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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