发明名称 |
FUSION PROTEIN CAPABLE OF CONTROLLING CALCIUM ION CONCENTRATION IN CELLS BY LIGHT, AND USE THEREOF |
摘要 |
The present invention relates to a method and a kit for reversibly inhibiting a protein function using light-induced nanocluster formation, and provides a fusion protein, wherein a light-induced heterodimerized protein is connected to the N-terminal or C-terminal of stromal interaction molecule 1 (STIM1) protein or to a cytosolic fraction cleaved from the N-terminal of the STIM1 protein to a transmembrane domain. |
申请公布号 |
WO2013115482(A1) |
申请公布日期 |
2013.08.08 |
申请号 |
WO2012KR10979 |
申请日期 |
2012.12.17 |
申请人 |
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
HEO, WON-DO;LEE, SANG-KYU;KYUNG, TAE-YOON |
分类号 |
C07K19/00;A01K67/027;C12N15/62;C12N15/63 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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