发明名称 (3-aryl-1H-1,2,4-triazol-5-yl)-linked heterocycle derivatives
摘要 This invention is directed to compounds of formula I having the structure which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
申请公布号 US8501795(B2) 申请公布日期 2013.08.06
申请号 US201013515351 申请日期 2010.12.15
申请人 PUESCHL ASK;NIELSEN JACOB;KEHLER JAN;KILBURN JOHN PAUL;MARIGO MAURO;LANGGAARD MORTEN;H. LUNDBECK A/S 发明人 PUESCHL ASK;NIELSEN JACOB;KEHLER JAN;KILBURN JOHN PAUL;MARIGO MAURO;LANGGAARD MORTEN
分类号 A61K31/41 主分类号 A61K31/41
代理机构 代理人
主权项
地址