发明名称 |
(3-aryl-1H-1,2,4-triazol-5-yl)-linked heterocycle derivatives |
摘要 |
This invention is directed to compounds of formula I having the structure which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
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申请公布号 |
US8501795(B2) |
申请公布日期 |
2013.08.06 |
申请号 |
US201013515351 |
申请日期 |
2010.12.15 |
申请人 |
PUESCHL ASK;NIELSEN JACOB;KEHLER JAN;KILBURN JOHN PAUL;MARIGO MAURO;LANGGAARD MORTEN;H. LUNDBECK A/S |
发明人 |
PUESCHL ASK;NIELSEN JACOB;KEHLER JAN;KILBURN JOHN PAUL;MARIGO MAURO;LANGGAARD MORTEN |
分类号 |
A61K31/41 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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