发明名称 Piperidinyl derivatives as modulators of chemokine receptor activity
摘要 The present application describes modulators of MIP-1alpha of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein m, Q, T, W, Z, R1, R3, R4, R5, R5a and R5b, are as defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using the modulators of formula (I) are disclosed.
申请公布号 US8501782(B2) 申请公布日期 2013.08.06
申请号 US20080670016 申请日期 2008.07.23
申请人 GARDNER DANIEL S.;DUNCIA JOHN V.;HYNES JOHN;DHAR T.G. MURALI;CARTER PERCY H.;SANTELLA JOSEPH B.;BRISTOL-MYERS SQUIBB COMPANY 发明人 GARDNER DANIEL S.;DUNCIA JOHN V.;HYNES JOHN;DHAR T.G. MURALI;CARTER PERCY H.;SANTELLA JOSEPH B.
分类号 A61K31/4545;A61K31/451;A61K31/4525;A61K31/454;C07D211/52;C07D401/04;C07D401/12;C07D405/12 主分类号 A61K31/4545
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