发明名称 |
MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS |
摘要 |
The present invention discloses compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. |
申请公布号 |
EP2618831(A1) |
申请公布日期 |
2013.07.31 |
申请号 |
EP20110827336 |
申请日期 |
2011.09.20 |
申请人 |
ENANTA PHARMACEUTICALS, INC. |
发明人 |
OR, YAT SUN;MA, JUN;WANG, GUOQIANG;LONG, JIANG;WANG, BIN |
分类号 |
C07K5/097;A61K38/21;C07K5/062;C07K5/08;C07K5/083 |
主分类号 |
C07K5/097 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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