| 发明名称 |
Hepatitis C virus replicons and replicon enhanced cells |
| 摘要 |
<p>The present invention features nucleic acid containing one or more adaptive mutations, and HCV replicon enhanced cells. Adaptive mutations are mutations that enhance HCV replicon activity. HCV replicon enhanced cells are cells having an increased ability to maintain an HCV replicon.</p> |
| 申请公布号 |
EP2050822(B1) |
申请公布日期 |
2013.07.31 |
| 申请号 |
EP20080171549 |
申请日期 |
2002.01.16 |
| 申请人 |
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. |
发明人 |
DE FRANCESCO, RAFFAELE;MIGLIACCIO, GIOVANNI;PAONESSA, GIACOMO |
| 分类号 |
C12N15/40;G01N33/50;C07K14/18;C12N5/10;C12N7/00;C12N15/09;C12N15/51;C12N15/85;C12N15/86;C12Q1/02;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
C12N15/40 |
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