发明名称 INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES
摘要 <p>The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is -NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.</p>
申请公布号 SG191196(A1) 申请公布日期 2013.07.31
申请号 SG20130046438 申请日期 2011.12.22
申请人 LEO LABORATORIES LIMITED 发明人 GRUE-SOERENSEN, GUNNAR;LIANG, XIFU;HOEGBERG, THOMAS;MAANSSON, KRISTOFFER;VEDSOE, PER;VIFIAN, THOMAS
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