发明名称 BENZIMIDAZOLE CARBOXAMIDES AS RAF KINASE INHIBITORS
摘要 The present invention relates to benzimidazole carboxamides of formula (I), the use of the compounds of formula (I) as inhibitors of as inhibitors of one or more kinases, the use of the compounds of formula (I) for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient. Accordingly, the compound of Formula (I) or a pharmaceutically acceptable salt thereof is administered for the treatment of diseases mediated by one or more kinase phathways, preferably by the raf kinase pathway, especially cancers.
申请公布号 CA2531856(C) 申请公布日期 2013.07.30
申请号 CA20042531856 申请日期 2004.06.11
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 BUCHSTALLER, HANS-PETER;WIESNER, MATTHIAS;ZENKE, FRANK;AMENDT, CHRISTIANE;GRELL, MATTHIAS;SIRRENBERG, CHRISTIAN
分类号 C07D401/12;A61K31/4439;A61K31/506;A61P35/00;C07D403/12 主分类号 C07D401/12
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