| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to pharmaceutical industry, namely to a solid pharmaceutical composition for oral administration on the basis of taxane. The solid pharmaceutical composition for oral administration contains amorphous taxane, a hydrophilic carrier and a surfactant (sodium dodecylsulphate (SDS)), with specific weight proportions of taxane and the carrier with taxane, the carrier and the surfactant found in a solid dispersion. The use of the composition for preparing a drug for treating a neoplastic disease. A method for preparing the pharmaceutical composition.EFFECT: pharmaceutical composition is characterised by higher solubility and higher dissolution rate of taxane.16 cl, 21 dwg, 18 tbl, 5 ex |
