| 发明名称 |
Novel Tetrahydronaphalene Antagonists to the Thromboxane A2 (TP) Receptor |
| 摘要 |
The present invention relates to TP receptor antagonists, which have the ability to bind to TP receptor and optionally cross the blood brain barrier. The invention also provides compositions and methods for treating a disorder wherein activation of TP receptor is detrimental.
|
| 申请公布号 |
US2013190370(A1) |
申请公布日期 |
2013.07.25 |
| 申请号 |
US201113812793 |
申请日期 |
2011.07.27 |
| 申请人 |
TROJANOWSKI JOHN Q.;LEE VIRGINIA M.Y.;BRUNDEN KURT R.;SMITH AMOS B.;HURYN DONNA M.;BALLATORE CARLO;HOGAN ANNE-MARIE;PISCITELLI FRANCESCO;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
TROJANOWSKI JOHN Q.;LEE VIRGINIA M.Y.;BRUNDEN KURT R.;SMITH AMOS B.;HURYN DONNA M.;BALLATORE CARLO;HOGAN ANNE-MARIE;PISCITELLI FRANCESCO |
| 分类号 |
C07C311/20;A61K31/18;A61K31/196;A61K31/216;A61K31/357;A61K31/41;A61K45/06;C07D257/04;C07D317/28 |
主分类号 |
C07C311/20 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
