NOTCH INHIBITION IN THE TREATMENT AND PREVENTION OF OBESITY AND METABOLIC SYNDROME
摘要
The present invention is directed to methods of treating or preventing obesity by administering agents that inhibit the NOTCH signaling pathway. Antibodies that inhibit the binding of Delta like 4 ligand (Dll4) to NOTCH receptors may be used for this purpose.
申请公布号
EP2493497(A4)
申请公布日期
2013.07.24
申请号
EP20100827551
申请日期
2010.10.29
申请人
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
发明人
AIKAWA, MASANORI;FUKUDA, DAIJU;MIYAZAKI, TETSURO;AIKAWA, ELENA
