MUSSEL ADHESIVE PROTEIN-ADDED BRUSHITED BONE GRAFT SUBSTITUTE

摘要

PURPOSE: A brushite substitute for a bone graft is provided to be developed as an ideal substitute for a bone graft by improving water-absorption properties. CONSTITUTION: A brushite substitute for a bone graft includes mussel adhesion protein. The mussel adhesion protein is fp-151 protein. The brushite is based on a beta-tricalcium phosphate/monocalcium phosphate monohydrate. A method for manufacturing the brushite substitute for a bone graft comprises the following steps. The mussel adhesion protein fp-151 is manufactured. A hardening solution is made using the mussel adhesion protein fp-151. The hardening solution and beta-tricalcium phosphate/monocalcium phosphate monohydrate are mixed. The mixture is molded.