发明名称 SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES
摘要 Substituted diaryl compounds of the Formulae (I, II, III), where the variables are as defined in the claims, and their pharmaceutically acceptable derivatives, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, including A.beta. amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment are provided.
申请公布号 CA2566090(C) 申请公布日期 2013.07.23
申请号 CA20052566090 申请日期 2005.05.12
申请人 PROTEOTECH, INC. 发明人 SNOW, ALAN D.;NGUYEN, BETH P.;LAKE, THOMAS P.;CASTILLO, GERARDO M.;WEIGELE, MANFRED
分类号 C07C311/08;A61K31/167;A61P25/28;C07C235/56;C07C237/40;C07D235/26 主分类号 C07C311/08
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