发明名称 |
PHARMACEUTICAL COMPOSITIONS FOR PREVENTING AND TREATING MYOCARDITIS COMPRISING SOLUBLE RAGE AS ACTIVE INGREDIENT |
摘要 |
PURPOSE: A pharmaceutical composition for preventing or treating myocarditis is provided to effectively reduce inflammation and to treat myocarditis. CONSTITUTION: A pharmaceutical composition for preventing or treating myocarditis contains soluble receptor for advanced glycation end products (sRAGE) as an active ingredient, with an amino acid sequence of sequence number 1 which binds to a ligand of RAGE. The sRAGE interrupts a bond between RAGE and the ligand of RAGE. The sRAGE is conjugated with a heavy chain of immunoglobulin G and an Fc region of an antibody.
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申请公布号 |
KR20130082472(A) |
申请公布日期 |
2013.07.19 |
申请号 |
KR20130003340 |
申请日期 |
2013.01.11 |
申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY |
发明人 |
PARK, SUNG HA;YANG, WOO IN;CHOI, DONG HOON;KIM, SE HOON;HONG, SUNG YU |
分类号 |
A61K38/16;A61K31/7105;A61K48/00;A61P9/04 |
主分类号 |
A61K38/16 |
代理机构 |
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